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These can decrease bleeding in up to 70% of women with minimal side effects and can often lead to no bleeding at all while the IUD is in place

Source: O'Leary, F., & Samman, S

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The dose was titrated on 4 weekly bases from 3 to 7 and 7 to 14 mg in their respective arms [Table 1].[16] Significant HbA1c reduction has been seen with all three doses 3, 7 and 14 mg in comparison to placebo whereas weight reduction was significant with 7 and 14 mg in comparison to placebo