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Within mitochondria, SOD2 plays a key role in converting O 2 to H 2 O 2 , which is subsequently reduced to water by glutathione peroxidases (GPx) and peroxiredoxins (Prx) [178]

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Therefore, it is essential to explore the transcriptional patterns in different populations of macrophages in various organs to gain a deeper understanding of their influence on ferroptosis sensitivity

The Roles of NRF2 in Modulating Cellular Iron Homeostasis

Current research does not support the claim that glutathione promotes hair loss