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N Engl J Med [internet] 379(23):22372245

A well-rounded diet, rich in protein, can help maximize the benefits of GLP-1 medications by maintaining your energy levels, supporting muscle retention, and preventing potential nutrient deficiencies

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Patients in the study were receiving dulaglutide (7), semaglutide injection (27), semaglutide oral (3), and tirzepatide (23)

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Below is a side-by-side comparison: The Glucagon receptor in Retatrutide may push the body to increase its energy expenditure, which Tirzepatide does not directly address