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N-Dimethyl formamide European restriction demands solvent substitution in research and development

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Images of syringes, one image of a complete capped needle/syringe combo, and a close-up image of a syringe with the base of the cap visible

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Such salts can be prepared according to traditional methods, for example by mixing L-carnitine with L-lysine in the form of hydrochloride in water and crystallization of the resulting salt by addition of an organic polar solvent immiscible in the water

doi: 10.1053/j.jrn.2017.11.007 19 BobotM.ThomasL.MoyonA.FernandezS.McKayN.BalasseL.et al