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A standard multivitamin may be all that is needed to correct a mild vitamin B12 deficiency

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It did both of these things while crossing the blood-brain barrier and maintaining a plasma half-life exceeding 6 hours, which means sustained brain exposure from a single administration

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Levodopa and cobalamin-related neurotoxic metabolites and benefits of COMT inhibitors The breakdown of LDopa through COMT requires methyl group transfer, leading to the formation of the stable compound 3-O-MethylDopa (Mller and Riederer 2023)

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