Interestingly, both US and U.K
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If you weigh 200 pounds, that is 100 ounces daily
In the EDICT trial, 221 drug-naive patients with recently diagnosed T2D were randomized to initial simultaneous therapy comprising a combination of agents known to improve insulin secretion and sensitivity (metformin, pioglitazone, and exenatide) or treatment with sequential therapy (i.e., an escalating dose of metformin followed by sequential addition of a sulfonylurea and insulin glargine)