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AOD-9604 has no approved therapeutic use anywhere in the world

NNMT sits between NAD+ metabolism and one-carbon methylation metabolism, pathways that support redox reactions, DNA repair, and transcriptional regulation

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Because it targets the metabolic process directly rather than suppressing appetite through the central nervous system, it doesnt cause the jittery feeling associated with many weight loss stimulants

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However, most cases are due to excess supplementation or due to a functional deficiency, where the person is actually deficient in B12