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Increased RGD uptake by tumor cells could potentially occur due to the binding affinity of RGD to integrins

doi: 10.1017/S0317167100033497 [DOI] [PubMed] [Google Scholar] 219.Zaeem Z, Zhou L, Dilli E

Peptides provide less dramatic but more accessible regenerative support

USA 110 , 47384743 (2013)

Because FOXO4-DRIs mechanism depends on disrupting the FOXO4p53 interaction, and because this interaction is only operative in cells with elevated FOXO4 expression, the compound preferentially targets the senescent cell population leaving FOXO4-low non-senescent cells largely unaffected

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