In fact her boss, Mads Krogsgaard Thomsen, remembers that top management gave them only one year 'to come up with a GLP-1 candidate for daily administration to people with type 2 diabetes' (Holst 2024)
Important cautions: Personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2: GLP-1s are contraindicated History of pancreatitis: Discuss risks carefully with your doctor Gallbladder issues: GLP-1s may increase gallstone risk Severe gastrointestinal disease: May worsen symptoms Pregnancy plans: Not recommended if youre trying to conceive Can GLP-1 mess with hormones? GLP-1s arent hormone therapy
Medicina (Kaunas)
The patients who maintain results best are those who used the treatment period to build strong protein-forward nutrition habits, preserve muscle mass through resistance exercise, and work with a physician on a planned tapering and maintenance strategy
In the Veterans Health Administration (VHA) national dataset, an adjusted OR indicated no significant difference in pancreatitis occurrences between thiazolidinedione and incretin groups (adjusted OR, 0.94
Although they are typically mild and transient, these AEs can affect adherence and limit dose titration
