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Nucleic Acids Res 42, D444D449, doi: 10.1093/nar/gkt1008 (2014)
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Preclinical observations also suggest generally reduced brain levels of the major antioxidant glutathione (GSH), albeit data are not entirely consistent [decreased (16, 1822)

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In animals, unlike the deletion of Slc7a11 , the deletion of the GGT family member Ggt1 results in increased GSH levels in urine, reduced cysteine levels in tissues and perinatal lethality 24