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Description

That said, the mechanism by which the process is activated is slightly different for orforglipron (the active ingredient in Foundayo) than it is for other GLP-1s

The theoretical difference comes from retatrutide's glucagon activity

Glucose-dependent insulinotropic polypeptide receptor agonism may further augment insulinotropic and metabolic effects when combined with GLP-1 receptor activation

PMID: 28943235 Johannsson, G., et al