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Wiel, C
Labels such as psychogenic or psychosomatic are applied by doctors, in part, because of a statistical correlation with higher levels of depression and anxiety.[ref] However, the physiological and cellular changes in people with chemical sensitivities are measurable, statistically significant, and visible, strongly suggesting a physiological cause rather than a psychological cause.[ref][ref] On the other hand, there are several clinical trials using specific solvents or chemical odors that found no statistical change in measured parameters (e.g
Cellular focus includes macrophages, endothelial cells, microglia, and neurons
measured the GSH levels in the stratum corneum of the subjects and found that GSH in stratum corneum in acne patients was significantly lower than that of healthy controls.[] ROSACEA The UV radiation is a very well-known triggering and aggravating factor for rosacea.[] It is a potent inducer of ROS generation in the skin.[] In patients of rosacea, there is an increased ratio of oxidized to reduced glutathione compared with healthy subjects.[] A pilot, prospective, two-center, assessor-blinded study by Dall'Oglio et al
High-throughput metabolomics: Isocratic and gradient mass spectrometry-based methods
