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Dose escalation schedules in GLP-1-based therapies are typically gradual precisely to allow the body to adapt and to minimise GI side effects a principle acknowledged in NICE guidance on approved agents (see NICE TA875)

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Consequently, this supplementation effectively reduced the oxidative stress levels in tissues, as compared to mice supplemented with vitamin D alone [44,69,70]

It is used to treat vitamin B deficiencies, nerve pain, and fatigue