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A second collagenase injection was administered three days later

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Seven reported feeling relief for more than six monthsmoderately encouraging, but hardly the large-scale human trial typically required for drug approval

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These findings validate the therapeutic targeting of the system Xc pathway, although challenges related to tumor selectivity and potential systemic toxicity remain

The weight loss curves had not plateaued at week 26, suggesting that longer treatment periods would yield even greater reductions