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Semaglutide, as a once weekly subcutaneous injection for weight management, effectively reduces body mass index (BMI) while improving hyperglycemia, elevated alanine aminotransferase levels, hyperlipidemia, and quality of life in youth with obesity [26]

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Instead of jumping straight into the clinical protocol, microdosing begins at doses as low as 0.5 mg or even 0.25 mg, then increases gradually over extended timelines