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Reduced bloating, gas, and post-meal discomfort

Similarly, Sirt4 regulates lipid metabolism and metabolic flux through its influence on malonyl CoA decarboxylase and pyruvate dehydrogenase, while also modulating mitochondrial signaling via AMPK-PGC1 and PPAR pathways

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Phase 2 Type 2 Diabetes Trial The Lancet (2023) A parallel Phase 2 trial published in The Lancet assessed retatrutide in 281 participants with type 2 diabetes over 36 weeks