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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Redman LM, Smith SR, Burton JH, Martin CK, Ilyasova D, Ravussin E

Lateral allosterism in the glucagon receptor family: glucagon-like peptide 1 induces G-protein-coupled receptor heteromer formation

There is now an urgent need to test metabolic approaches in controlled clinical trials

Cataplerosis Given that metabolic intermediates from various pathways can be added to the TCA cycle via the process of anaplerosis, it is important that these intermediates be effectively oxidized and/or disposed of so as to prevent their accumulation in the mitochondrial matrix

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These genetic insights may help provide context for why certain individuals benefit from creatine while others face higher riskthough genetic predisposition does not predict exact medication response or supplement efficacy