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Bottom line SURMOUNT-4 ended the course-of-treatment story

If side effects are intolerable on one, switching to the other is a reasonable option

Primarily indicated for type 2 diabetes: Ozempic Rybelsus Trulicity Victoza Byetta Bydureon Adlyxin Primarily indicated for chronic weight management: Wegovy Saxenda Zepbound Some active ingredients, such as semaglutide and tirzepatide, are available in separate branded formulations that carry different FDA-approved indications

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doi: 10.1186/1742-4933-2-14 49 JiangLSongXYanLLiuYQiaoXZhangW

Contraindication Signals Standard conservative practice excludes anyone with active gastrointestinal disease, type 1 diabetes, prior pancreatitis, medullary thyroid carcinoma history, or active cancer from any retatrutide protocol