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In the SURMOUNT-1 trial, patients lost an average of 22.5% of body weight over 72 weeks

(2024, Clinical Diabetes) Study Design : Narrative review summarizing the ongoing Phase 3 clinical development program

Semaglutide can also cause dizziness

As for side effects, one function of clinical trials is to determine the safety of the drug, including uncovering side effects

The effects of the leptin-GLP-1 interaction may be governed by intracellular signaling pathways, including those involving phosphorylated STAT3 and PTP1B

Nevertheless, under the administration of a DPP-4 inhibitor, pasireotide drastically inhibited GLP-1 secretion