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Metabolomics 12 , 109, (2016)

595 A study suggests that the activation of PARP may lead to cell death through ATP consumption and enhancement of the inflammatory cascade in mice

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Activated and polarized microglia typically exhibit the pro-inflammatory M1 phenotype and produce pro-inflammatory cytokines, contributing to neuronal dysfunction and reinforcing disease-related behaviors, all of which are related to psychiatric disorders (64, 65)

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Activation of Nrf2 signaling protects hypoxia-induced HTR-8/SVneo cells against ferroptosis