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Description

Activation of Gs-linked -adrenergic receptors by catecholamines further increases cAMP levels, while Gq-coupled receptors, such as the vasopressin 1b receptor (V1bR), activate phospholipase C (PLC) and produce inositol trisphosphate (IP3), leading to increased intracellular calcium and enhanced glucagon release ( Glucagon secretion from pancreatic -cells is also heavily regulated by intra-islet paracrine signals

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