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30 , 10551074.e1058 (2019)

In a 14-month randomized, double-blind, placebo-controlled trial that administered a daily micronutrient-fortified beverage (details lacking) or placebo to 608 children (aged 6-15 years) in India, micronutrient supplementation was linked to improved scores on one measure of attention and concentration (Knox Cube test) but not on another assessment (Letter Cancellation test) (104)

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This distinct distribution pattern suggests that insulin and IGF-1 may influence different neuronal circuits and processes pertinent to depression