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For these individuals, introducing supplemental sulfur donors like glutathione or N-Acetyl-l-Cysteine (NAC) can sometimes trigger paradoxical mast cell reactions, causing symptom flares, hives, or worsened tachycardia
(Asterisks indicate nominal p-value * = 0.05, ** = 0.01, *** = 0.001, two-sided Fisher exact test.)