If you are experiencing side effects that feel severe, persistent, or worrying at any point, contact your healthcare professional promptly
For weekly formulations like semaglutide and tirzepatide, the peak plasma concentration arrives 1 to 3 days after injection
Dani SS, Makwana B, Khadke S, Kumar A, Jhund P, Nasir K, Sattar N, Al-Kindi S, Fonarow G, Butler J, Bhatt DL, Kosiborod MN, Nohria A, Ganatra S (2025) An observational study of cardiovascular outcomes of tirzepatide vs glucagon-like peptide-1 receptor agonists
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Some patients report loss of appetite
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