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Recent studies using tissue/cell-specific gene knockout mouse models and cell culture techniques have clearly demonstrated that locally produced IGF-I is more critical than the systemic IGF-I in supporting embryonic and postnatal skeletal development and bone remodeling

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Roh JH, Jiang H, Finn MB, Stewart FR, Mahan TE, Cirrito JR, et al

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Ipamorelin is a hormone secretagogue

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