A Matter of Taste In Semaglutide and Taste in Women With Obesity and Polycystic Ovary Syndrome: A Randomized Placebo-Controlled Study , published in JCEM in May, Andrej Jane, MD, PhD, of the Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, in Zaloska, Slovenia, and team sought to better understand the complex, often inconsistent relationship between obesity and taste perception, coupled with a major evidence gap on how GLP-1 analogues like semaglutide affect taste function
The medication works primarily by regulating appetite, slowing gastric emptying, and influencing glucose metabolism through GLP-1 receptors
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doi: 10.1038/s41573-021-00233-1
This action is working in conjunction with the brain as it influences appetite suppression and energy expenditure by interacting with neuronal circuits that regulate hunger and fullness (Zhang et al