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In a study published in the Journal of Cutaneous and Aesthetic Surgery, the maximum dose used in one sitting was 5 g (6)

The next report in 1983 carried out in by a Leicester GP training practice

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Hempill-Bryant explains that babies born to B12 deficient mothers will also be deficient in B12, especially if they are then exclusively breastfed. A study in the Journal of Child Neurology found that the most severe cases of B12 deficiency can lead to weakness, failure to thrive, afebrile seizure, developmental delay, nystagmus, tremors, and involuntary movement among young babies

This ongoing attention to detail helps to eliminate experimental variables and supports reproducible results in controlled research environments, just like how standardized protocols in academic research facilities maintain consistency across multiple lab studies

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