10.1038/s41598-021-98819-7 Sci Rep
Rule 3 Documentation Must Name the Type, Cause, and Lab Evidence
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LY3437943 (Retatrutide): discovery to clinical proof of concept (triple GLP-1/GIP/glucagon agonist, preclinical mechanism) Nature Reviews Endocrinology (2024) Multi-receptor agonists for metabolic disease (mechanism of GLP-1/GIP/glucagon co-activation) Diabetes Care (2024) Incretin-based therapies: GLP-1, GIP, and glucagon receptor pharmacology (metabolic pathways, energy expenditure) NEJM (2023) Supplementary Material Jastreboff et al
American Society of Anesthesiologists+2PubMed+2 A 2025 cohort study did not find a major increase in postoperative aspiration pneumonia among GLP-1 users overall, which is reassuring, but care still needs to be tailored to the individual
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