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In REDEFINE 1 (overweight/obesity without T2D), CagriSema achieved mean weight reductions of 20.4-22.7% (vs 2.3-3.0% placebo) at 68 weeks, with 53.6% and 34.7% of patients achieving 20% and 25% weight loss, respectively

Oncogene 28 , 40534064 (2009)

79 On the other hand, ATP-dependent chromatin-remodeling complexes guide gene expression by restructuring the nucleosome

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