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Although Metformin is not FDA-approved for longevity, the agency has authorized its investigation in aging through the TAME (Targeting Aging with Metformin) Triala landmark study exploring its potential to slow age-related decline and extend healthspan

Glorieux C, Liu S, Trachootham D, Huang P

Triple hormone receptor agonist Retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial

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Women who are pregnant, nursing or think they may be pregnant should not take COCs

However, it is crucial to understand that microdosing GLP-1 is not an evidence-based practice and lacks formal clinical trial data supporting its efficacy or safety