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It represents a spectrum of liver conditions, ranging from simple steatosis to non-alcoholic steatohepatitis (NASH), which involves inflammation and liver cell damage, and can progress to fibrosis, cirrhosis, and hepatocellular carcinoma

doi: 10.1038/npp.2012.78 148 HoyeM

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In addition, we examined the role of glutathione transporter, xCT, in APR-246 treatment

Henninge et al

Located in the nucleus, the active NF-B subunits primarily regulate inflammatory genes, making them a crucial regulator of the immune response associated with inflammatory bowel disease (IBD) (Shahid et al