glp-1 long term effects Unique and Shared of Bariatric Surgery and GLP-1RA glp-1 side effects long term

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492 Targeting less conserved substrate binding sites, as opposed to ATP binding sites, might offer advantages in terms of drug specificity, functional regulation, and safety

In low oxygen situations (hypoxia, ischaemia) lactate increases several-fold as its conversion from pyruvate in the lactate dehydrogenase reaction is essential to regenerate NADH needed to maintain glycolysis [59]

Increasing GLP-1 in the postprandial period correlates with the increase in blood flow in brain areas related to satiety, such as the hypothalamus and areas of the prefrontal cortex [53]

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doi: 10.1073/pnas.0712140105 193