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Sulfate conjugation reactions catalyzed by SOT generate 3-phosphoadenosine 5-phosphate (PAP), a molecule that participates in the organelle-nuclear retrograde signaling, if not dephosphorylated by the SAL1 phosphatase ( FIGURE 1 While many essential steps of the sulfate assimilation and cysteine, methionine and glutathione biosynthesis pathways occur exclusively in plastids, a few enzymes present in the cytosol and mitochondria also come into play, which necessitates a concerted action between enzymes present in different subcellular compartments and intracellular transporters
BMJ 318 , 13751381 (1999)
10.1111/j.1365-2133.2006.07165.x [DOI] [PubMed] [Google Scholar] 72.Esteva A et al
10.1160/TH05 32
Ferreri, Ph.D
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