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UV irradiation of skin induces p53 within the epidermis and directly upregulates expression of the precursor protein proopiomelanocortin (POMC)

But it is clients own choice also for selection and desired colour

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10.1111/j.1610-0387.2009.07120.x [DOI] [PubMed] [Google Scholar] 73.Weisenseel P, Reich K, Griemberg W, Merten K, Grschel C, Gomez NN, et al

Both professions increasingly specialize in weight management, metabolic health, and GLP-1 therapy, often bringing detailed patient education and follow-up care