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The effects of water volume and post-dose fasting on SNAC exposure in the dosing conditions trial are shown in Supplementary Figs

10.1056/NEJMoa2032183 [DOI] [PubMed] [Google Scholar] 21

Warnings: Patients with early Leber's disease (hereditary optic nerve atrophy) may experience severe and rapid optic atrophy when treated with vitamin B12. Additionally, treating severe megaloblastic anemia with vitamin B12 can lead to fatal hypokalemia due to increased erythrocyte potassium requirements

Once-weekly cagrilintide for weight management in adults with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled phase 2 trial

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