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A recent meta-analysis of mixed evidence (5 RCTs 52,183,184,185,186 and 1 cohort study 187 ) in 2,071 people with T2DM or Parkinsons disease suggested antidepressant efficacy of the GLP-1RAs exenatide and liraglutide over 2452 weeks 188

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PMID: 38858523 | doi:10.1038/s41591-024-03018-2 Pasqualotto E et al

No path to weight loss is complete without an understanding of your body's nutrient needs and how best to meet them

Population differences between trials also deserve consideration

doi: 10.1371/journal.pone.0289616