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Extracellular acidification promoted solute uptake, a property of OATP2B1 that bears relevance to the small intestinal environment in which the transporter is expressed on the apical membrane of the enterocytes

In a clinical trial of AIDS patients were treated with 1.8 g/day of NAC for two weeks with the glutathione status monitored in plasma and lymphocytes

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Screening includes serum B12, RBC thiamine, and PLP (B6) tests, plus homocysteine and MMA levels