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Roles of the metazoan TrxR1 system in signaling It is possible that the metazoan TrxR arose specifically for regulation of signaling pathways and not as an improved means of sustaining redox homeostasis

J Biol Chem 284:2500425014 Anello M, Lupi R, Spampinato D et al (2005) Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients

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doi:10.2147/JPR.S143500

Sorafenib as a ferroptosis-related clinical drug has been approved by the United States Food and Drug Administration for the treatment of ovarian cancer (98)

10.1128/aem.63.9.3732-3735.1997 Appl