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Strasser B, Becker K, Fuchs D, Gostner JM

The Menopause Society (2025)

But here's the key insight: the GLP-1 receptor doesn't have one single "on" signal

Specifically, higher intake of omega-3 fatty acids, particularly EPA and DHA, was associated with reduced depressive symptoms and improved inflammatory profiles (72)

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As mentioned, one trial also indirectly compared the effectiveness of 1mg/weekly semaglutide and 4.5mg/weekly dulaglutide