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They are included solely for background reading and must not be interpreted as evidence of safety, efficacy, or suitability for human use
Hepatology 67 , 12611269 (2018)
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However, caution should be taken when interpreting these results because the primary analyses in these studies [19, 20] were based on the as-treated scenario, which may limit the applicability of these results to patients with optimal treatment adherence
moderate renal impairment (eGFR 30-45 ml/min) has been observed to increase plasma levels of sitagliptin 2-fold, and severe renal impairment can increase plasma levels 4-fold