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It belongs to a group of drugs called glucagon-like peptide-1 receptor (GLP-1) agonists

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In response to various PAMPs and DAMPs, NLRP3 oligomerizes with the adapter protein ASC to form a high molecular weight complex that recruits and cleaves pro-caspase-1, activating it and driving the maturation of IL-1 and IL-18, GSDMD cleavage, and pyroptosis

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From Phase I through Phase III, ecnoglutide injection has consistently demonstrated a favorable safety profile and strong efficacy, with the findings published in leading metabolic journals, underscoring its potential as a promising therapy for patients with metabolic diseases