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Impairment of the energy metabolism of the mitochondrion is said to be involved in migraine pathogenesis

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J Biol Chem 294:48434853 Tanaka Y, Gleason CE, Tran PO, Harmon JS, Robertson RP (1999) Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

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However, excessive inhibition of autophagy may lead to the accumulation of cellular debris, which could be detrimental to neuroprotection

Mounjaro cost without insurance Like Ozempic, Mounjaro is also FDA-approved for type 2 diabetes, but patients often take it for weight management (off-label)