Kopel E, Levi A, Harari M, Ruzicka T, Ingber A
Serotonergic Drugs The concomitant use of opioids with other drugs that affect the serotonergic neurotransmitter system, such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), triptans, 5-HT3 receptor antagonists, drugs that affect the serotonin neurotransmitter system (e.g., mirtazapine, trazodone, tramadol), certain muscle relaxants (i.e., cyclobenzaprine, metaxalone), and monoamine oxidase (MAO) inhibitors (those intended to treat psychiatric disorders and also others, such as linezolid and intravenous methylene blue), has resulted in serotonin syndrome (see PRECAUTIONS, Information for Patients)
Scotton WJ, Mollan SP, Walters T, Doughty S, Botfield H, Markey K, et al
Alt Med Rev 1997;2(3):177-183
En effet, sous laction des enzymes de certaines bactries du microbiote intestinal, la carnitine prsente dans le tube digestif est susceptible dtre transforme en trimthylamine (TMA)
Branched-chain amino acid metabolic reprogramming orchestrates drug resistance to EGFR tyrosine kinase inhibitors
