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What they found: Significant improvement in sexual desire vs placebo Improvement in arousal and genital congestion No serious side effects Mild nausea in some subjects Why it matters: PT-141 (Bremelanotide) is an MC4R-selective fragment of Melanotan II optimized for sexual function

In all cases, IGF-1 DES is more potent in stimulating these changes than IGF-1, indicating that the peptide might be an effective adjuvant to antibiotics and other treatments used in the setting of infectious disease

It produces inflammatory cytokines, including TNF-alpha and interleukin-6, that circulate throughout the body and contribute to widespread inflammation

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