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Once this interaction is disrupted: p53 is released from the nucleus Cellular self-destruction pathways are activated Senescent cells undergo apoptosis This selective mechanism has made FOXO4-DRI one of the most studied senolytic peptides in modern aging research

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Antonio J et al

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Compared to patients with scattered areas of fibroglandular density, women with heterogeneously dense breasts have a 1.28-fold increased risk of breast cancer, while women with extremely dense breasts have a 2.11-fold increased risk of breast cancer [19]

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