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Abrupt cessation after 12+ weeks of daily dosing can suppress endogenous growth hormone pulsatility for two to three months

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Materials and Methods Cell lines FlpIn 293 cells (Life Technologies) with low passage number were transfected with empty pcDNA5/FRT vector or pcDNA5/FRT vector containing either wild-type MRP1, wild-type MRP2, or MRP1/MRP2 chimeras and mutants

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