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When the neurons in the substantia nigra are damaged in large numbers, the loss of dopamine prevents normal function in basal ganglia and causes the motor symptoms of PD: tremor, rigidity, impaired balance, and loss of spontaneous movement [56]

conceived the idea of the manuscript and organized its plan

As an endoplasmic reticulum (ER)-resident chaperone and oxidoreductase, P4HB plays an essential role in protein folding and disulfide bond formation

(2020) prepared betulinic acidloaded nanoliposomes and evaluated their anticancer effects on colorectal cancer cell lines

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This feedback mechanism not only influences tumor cell growth and survival but also affects the tumor response to therapy