The findings deliver early evidence that semaglutide may offer a dual benefit, targeting obesity and key reproductive challenges associated with the condition, including irregular menstruation and impaired fertility. Clare Thompson, MBBS, BSc, nMRCGP Separately, a review of five randomized controlled trials presented at ENDO 2026 found that GLP-1 drugs, such as semaglutide and liraglutide, do not appear to harm male fertility and may even improve testosterone levels and sperm quality in some men with obesity
Users consistently praise the speed of onboarding, with some receiving prescriptions on the same day they signed up
This guide breaks down the nuances by medication, so you know exactly where to inject, why it matters, and how to rotate your sites correctly for long-term safety and success
Fatigue usually subsides as your body adapts to the metabolic changes semaglutide triggers
Understanding why they happenand how to reduce themcan help you stay comfortable and confident as you continue seeing results
From there, the GLP-1 medication enters the bloodstream and begins working in much the same way as an injection
