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However, due to their high price tagoften $1,000 to $1,500 monthlymany employers are still debating whether to include them in benefits plans

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Patients should contact their healthcare provider if they experience severe or persistent heartburn that does not respond to conservative measures or over-the-counter treatments within 1-2 weeks, as this may indicate more significant gastroesophageal pathology requiring investigation

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Discontinuation was defined as a gap of more than 90 days between the end of one prescription supply and the next fill, or between the end of supply and the close of the one-year follow-up window

Organic compounds Phenolic compounds Phenolic compounds are a heterogeneous group of plant and fungal metabolites [14]