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Documentation of the injection should be included in the patient's medical record, and the patient should be informed about the possible side effects of the medication
#EliLilly #Retatrutide #GLP1 #GIP #Glucagon #ObesityTreatment #Phase3 #TRIUMPH1 #WeightLossDrugs Eli Lillys retatrutide, a GIP/GLP-1/glucagon triple agonist, met Phase 3 endpoints, delivering 28.3% weight loss over 80 weeks in TRIUMPH-1
We also thank the eQTLGen consortium, the FinnGen team, and other researchers and participants for providing publicly available data for this analysis
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We found here that agonist trafficking properties, as well as insulin secretion, mirrored -arrestin recruitment propensity, contrasting with some 14,33 (but not all 34 ) previous work suggesting that -arrestins do not impact GLP-1R trafficking 14,34,35 , as well as reports of coupling of GLP-1R to insulin secretion via -arrestin-1 14 (although not -arrestin-2 60 )
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